Certificate of Analysis
Each batch of Tα1 undergoes rigorous third-party testing to ensure purity and identity verification. View the full lab report below.
Thymosin Alpha-1
99%+ purity, independently tested · View COA
Ships same day when ordered before 2 PM EST · tracked and discreet
Thymosin Alpha-1 (Tα1) is a naturally occurring 28-amino acid peptide originally isolated from thymic tissue. This research-grade immunomodulatory peptide is extensively studied for its effects on T-cell maturation, dendritic cell activation, and immune system regulation in laboratory settings.
99%+
10mg
Bundle & Save
Order before 2 PM EST, ships the same day. Fast, fully tracked, and sent in discreet, secure packaging. Free shipping on orders over $99.
Purity Guarantee. If independent third-party testing doesn't confirm our stated purity standards, you get a full refund plus a free replacement.
For Research Use Only
Intended for in-vitro research only. Not for human consumption. Must be 21+.
Specifications
Certificate of Analysis
Each batch of Tα1 undergoes rigorous third-party testing to ensure purity and identity verification. View the full lab report below.
Overview
Biochemical Characteristics
Thymosin Alpha-1 is an N-terminally acetylated peptide with an acidic isoelectric point. The acetylation protects against aminopeptidase degradation, contributing to its stability in experimental models.
Research Applications
Pathway / Mechanistic Context
Preclinical Research Summary
Form & Analytical Testing
Mechanisms of Action
T-Cell Maturation - Promotes differentiation and maturation of T-lymphocytes from precursor cells
Dendritic Cell Activation - Enhances dendritic cell function and antigen presentation capabilities
Toll-Like Receptor Signaling - Modulates TLR2, TLR9, and downstream immune signaling pathways
Cytokine Modulation - Regulates production of IL-2, IFN-α, IFN-γ, and other immune mediators
Research Applications
1Immunomodulation Research
Thymosin Alpha-1 is primarily studied for its effects on immune system regulation and T-cell biology.
Key Research Findings
- Promotes T-lymphocyte maturation from precursor cells
- Enhances natural killer (NK) cell cytotoxicity
- Modulates Th1/Th2 balance toward Th1 responses
- Increases production of IL-2 and IFN-γ in immune cells
2Dendritic Cell Research
Research explores effects on dendritic cell function and antigen presentation.
Key Research Findings
- Activates dendritic cells through TLR signaling
- Enhances antigen uptake and processing
- Promotes dendritic cell maturation markers
- Improves cross-presentation capabilities
3Innate Immunity Research
Studies investigate effects on innate immune responses and host defense.
Key Research Findings
- Activates Toll-like receptor 2 and 9 pathways
- Enhances macrophage phagocytic activity
- Modulates inflammatory cytokine production
- Supports innate-adaptive immune crosstalk
Supporting Research & Bibliography
The following peer-reviewed publications support the research applications described above. References are provided for informational purposes to assist researchers in their literature review.
Total references: 4
Note: The information provided is for research reference only. It summarizes published in-vitro, animal and, where cited, human clinical studies of the compound; findings from those studies are not claims about this product. This product is intended for laboratory research purposes only. Not for human or veterinary use.
Common questions
- What purity is Tα1, and how is it tested?
- Tα1 is supplied at 99%+ purity. Each production lot is tested by an independent third-party laboratory, with HPLC for purity and mass spectrometry for identity. Published certificates can be looked up by the lot number printed on your vial in our COA library.
- Does Tα1 come with a Certificate of Analysis?
- Certificates are published online rather than printed in the box. You can view and download the certificate on this page before you buy, and match the lot number on your vial to its certificate in the COA library. Our guide on how to read a peptide COA explains each section.
- How fast does Tα1 ship?
- Orders placed before 2 PM EST ship the same day from the United States, with tracking and discreet packaging.
- How should Tα1 be stored?
- Store at -20°C. Our storage and handling guide covers temperature, light and moisture in more detail.
- What if independent testing doesn't confirm the stated purity?
- Our Purity Guarantee covers it: if independent testing does not confirm the stated purity, you get a full refund and a free replacement.
- Is Tα1 for human use?
- No. Tα1 is sold strictly for laboratory research use only. It is not for human or veterinary use, and we do not provide dosing or administration guidance.
Research Use Only: This product is intended for laboratory research purposes only. Not for human or veterinary use. By purchasing, you confirm that you are a qualified researcher and will use this product in accordance with all applicable regulations.