Certificate of Analysis
Each batch of TB-500 undergoes rigorous third-party testing to ensure purity and identity verification. View the full lab report below.
TB-500 (Thymosin Beta-4)
99%+ purity, independently tested · View COA
Ships same day when ordered before 2 PM EST · tracked and discreet
TB-500 (Thymosin Beta-4 fragment) is a synthetic peptide representing the active region of Thymosin Beta-4. This research-grade peptide is extensively studied for its effects on tissue repair mechanisms, cell migration dynamics, and anti-inflammatory pathways in laboratory settings.
99%+
5mg
Bundle & Save
Order before 2 PM EST, ships the same day. Fast, fully tracked, and sent in discreet, secure packaging. Free shipping on orders over $99.
Purity Guarantee. If independent third-party testing doesn't confirm our stated purity standards, you get a full refund plus a free replacement.
For Research Use Only
Intended for in-vitro research only. Not for human consumption. Must be 21+.
Specifications
Certificate of Analysis
Each batch of TB-500 undergoes rigorous third-party testing to ensure purity and identity verification. View the full lab report below.
Research background
TB-500 and Thymosin Beta-4: Tissue Repair Research
Thymosin beta-4 is the main actin-sequestering protein in mammalian cells and a well-studied tissue repair molecule. What its active sites do, what the wound, cardiac and neurological models showed, what 'TB-500' refers to, and how to verify the material you are working with.
Overview
Biochemical Characteristics
TB-500 contains the central actin-binding domain (amino acids 17-23: LKKTETQ) critical for G-actin sequestration. This region enables modulation of cytoskeletal dynamics, facilitating cell migration and tissue remodeling in experimental models.
Research Applications
Pathway / Mechanistic Context
Preclinical Research Summary
Form & Analytical Testing
Mechanisms of Action
Actin Sequestration - Binds G-actin to regulate cytoskeletal polymerization dynamics
Cell Migration Promotion - Enhances keratinocyte and endothelial cell motility
Anti-Inflammatory Signaling - Reduces pro-inflammatory cytokine expression (TNF-α, IL-1β)
Stem Cell Recruitment - Activates tissue-resident progenitor cell populations
Research Applications
1Wound Healing & Tissue Repair
TB-500 demonstrates remarkable wound healing acceleration in research models.
Key Research Findings
- Accelerates wound closure in rat dermal injury models
- Promotes angiogenesis and new blood vessel formation
- Reduces scarring through modulation of collagen deposition in animal wound models
- Enhances keratinocyte migration to wound sites
2Cardiac Tissue Research
Cardiovascular research applications show promising results.
Key Research Findings
- Reduces infarct size in mouse models of ischemic injury
- Promotes cardiomyocyte survival under hypoxic conditions
- Stimulates cardiac progenitor cell differentiation
- Improves cardiac function in heart failure models
3Muscle & Connective Tissue
Research indicates significant effects on muscle and connective tissue healing.
Key Research Findings
- Accelerates muscle fiber regeneration in animal injury models
- Reduces fibrosis in animal muscle injury models
- Promotes tendon and ligament repair in preclinical models
- Studied for effects on tissue elasticity in connective tissue models
Supporting Research & Bibliography
The following peer-reviewed publications support the research applications described above. References are provided for informational purposes to assist researchers in their literature review.
Total references: 4
Note: The information provided is for research reference only. It summarizes published in-vitro, animal and, where cited, human clinical studies of the compound; findings from those studies are not claims about this product. This product is intended for laboratory research purposes only. Not for human or veterinary use.
Common questions
- What purity is TB-500, and how is it tested?
- TB-500 is supplied at 99%+ purity. Each production lot is tested by an independent third-party laboratory, with HPLC for purity and mass spectrometry for identity. Published certificates can be looked up by the lot number printed on your vial in our COA library.
- Does TB-500 come with a Certificate of Analysis?
- Certificates are published online rather than printed in the box. You can view and download the certificate on this page before you buy, and match the lot number on your vial to its certificate in the COA library. Our guide on how to read a peptide COA explains each section.
- How fast does TB-500 ship?
- Orders placed before 2 PM EST ship the same day from the United States, with tracking and discreet packaging.
- How should TB-500 be stored?
- Store at -20°C. Our storage and handling guide covers temperature, light and moisture in more detail.
- What if independent testing doesn't confirm the stated purity?
- Our Purity Guarantee covers it: if independent testing does not confirm the stated purity, you get a full refund and a free replacement.
- Is TB-500 for human use?
- No. TB-500 is sold strictly for laboratory research use only. It is not for human or veterinary use, and we do not provide dosing or administration guidance.
Research Use Only: This product is intended for laboratory research purposes only. Not for human or veterinary use. By purchasing, you confirm that you are a qualified researcher and will use this product in accordance with all applicable regulations.