Epithalon
Epithalon (Epitalon) is a synthetic tetrapeptide with the sequence Ala-Glu-Asp-Gly. This research compound has been studied for its potential effects on telomerase activation in laboratory settings.
99%+
10mg
Specifications
Extended Research Applications & Mechanisms
Scientific Profile
Epithalon (Epitalon) is a synthetic tetrapeptide with the sequence Ala-Glu-Asp-Gly, derived from the natural pineal gland peptide Epithalamin. It has been extensively studied for its potential effects on telomerase activation and cellular longevity.
Mechanisms of Action
Telomerase Activation - Stimulates telomerase enzyme activity
Pineal Gland Function - Normalizes melatonin production
Antioxidant Enhancement - Increases antioxidant enzyme activity
Gene Expression - Modulates age-related gene expression patterns
Research Applications
1Telomere & Cellular Aging Research
Epithalon is primarily studied for its effects on telomere biology and cellular senescence.
Key Research Findings
- Increases telomerase activity in somatic cells
- Extends telomere length in cultured fibroblasts
- Reduces markers of cellular senescence
- Improves cell proliferation capacity in aged cells
2Neuroendocrine Function
Research explores effects on pineal gland and hormonal regulation.
Key Research Findings
- Normalizes circadian rhythm patterns
- Restores melatonin secretion in aged subjects
- Modulates cortisol and other stress hormones
- Improves sleep architecture in research models
3Antioxidant & Protective Effects
Studies indicate enhanced cellular protection mechanisms.
Key Research Findings
- Increases superoxide dismutase activity
- Enhances glutathione peroxidase levels
- Reduces lipid peroxidation markers
- Protects against oxidative DNA damage
Supporting Research & Bibliography
The following peer-reviewed publications support the research applications described above. References are provided for informational purposes to assist researchers in their literature review.
Effect of Epitalon on pineal gland and melatonin level in aged macaques
Khavinson VK, Pendina AA, Efimova OA, et al.
Effect of the synthetic pineal peptide epitalon on spontaneous carcinogenesis in female C3H/He mice
Kossoy G, Anisimov VN, Ben-Hur H, et al.
Total references: 4
Note: The information provided is for research reference only. All research applications are based on in-vitro and animal studies. This product is intended for laboratory research purposes only. Not for human or veterinary use.
Research Use Only: This product is intended for laboratory research purposes only. Not for human or veterinary use. By purchasing, you confirm that you are a qualified researcher and will use this product in accordance with all applicable regulations.
