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HomeProductsSS-31 (Elamipretide)
SS-31 (Elamipretide)
Specialty Peptides

SS-31 (Elamipretide)

$69.00$55.0020% OFFIn StockChecking availability...

SS-31 (Elamipretide) is a synthetic cell-permeable tetrapeptide that selectively targets the inner mitochondrial membrane. This novel mitochondria-targeted antioxidant binds to cardiolipin, providing unique access to the electron transport chain for advanced mitochondrial research.

Purity

99%+

Size

10mg

1
COA Available
Lab Verified
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For Research Use Only (RUO)

This product is intended for in-vitro research applications only. Not for human or animal consumption, cosmetic use, or as a dietary supplement. All customers must be at least 21 years of age. It is the researcher's responsibility to handle materials in accordance with their institution's safety protocols and all applicable laws.

Specifications

Molecular Weight639.79 Da
SequenceD-Arg-Dmt-Lys-Phe-NH₂
AppearanceWhite lyophilized powder
StorageStore at -20°C
SolubilitySoluble in sterile water

Certificate of Analysis

Each batch of SS-31 undergoes rigorous third-party testing to ensure purity and identity verification. Download your COA instantly.

HPLC Purity Analysis
Mass Spectrometry Verification
Lot-Specific Documentation

Extended Research Applications & Mechanisms

Overview

SS-31 (Elamipretide) is a synthetic cell-permeable tetrapeptide that selectively targets the inner mitochondrial membrane. This mitochondria-targeting peptide selectively binds to cardiolipin.

Biochemical Characteristics

Sequence: D-Arg-Dmt-Lys-Phe-NH₂ (Dmt = 2',6'-dimethyltyrosine)
Molecular Formula: C₃₂H₄₉N₉O₅
Molecular Weight: 639.79 g/mol
CAS Number: 736992-21-5

Mechanisms of Action

1

Cardiolipin Binding - Selectively targets and stabilizes cardiolipin in inner mitochondrial membrane

2

ROS Reduction - Decreases electron leak and mitochondrial reactive oxygen species production

3

Electron Transport Optimization - Improves cytochrome c-cardiolipin interaction and bioenergetics

4

Membrane Stabilization - Prevents cardiolipin peroxidation and membrane damage

Research Applications

1Mitochondrial Dysfunction Research

Primary focus on restoring mitochondrial function in cellular and animal models.

Key Research Findings
  • Reduces mitochondrial ROS production by 30-50% in research models
  • Protects cardiolipin from peroxidation during oxidative stress
  • Restores ATP synthesis capacity in aged mitochondria
  • Prevents mitochondrial permeability transition pore opening

Note: The information provided is for research reference only. All research applications are based on in-vitro and animal studies. This product is intended for laboratory research purposes only. Not for human or veterinary use.

Research Use Only: This product is intended for laboratory research purposes only. Not for human or veterinary use. By purchasing, you confirm that you are a qualified researcher and will use this product in accordance with all applicable regulations.

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