Certificate of Analysis
Each batch of SS-31 undergoes rigorous third-party testing to ensure purity and identity verification. The lab report for the latest batch is being finalized.
SS-31 (Elamipretide)
99%+ purity, independently tested
Ships same day when ordered before 2 PM EST · tracked and discreet
SS-31 (Elamipretide) is a synthetic cell-permeable tetrapeptide that selectively targets the inner mitochondrial membrane. This novel mitochondria-targeted antioxidant binds to cardiolipin, providing unique access to the electron transport chain for advanced mitochondrial research.
99%+
10mg
Bundle & Save
Order before 2 PM EST, ships the same day. Fast, fully tracked, and sent in discreet, secure packaging. Free shipping on orders over $99.
Purity Guarantee. If independent third-party testing doesn't confirm our stated purity standards, you get a full refund plus a free replacement.
For Research Use Only
Intended for in-vitro research only. Not for human consumption. Must be 21+.
Specifications
Certificate of Analysis
Each batch of SS-31 undergoes rigorous third-party testing to ensure purity and identity verification. The lab report for the latest batch is being finalized.
Research background
What Is SS-31 (Elamipretide)? Mitochondrial Peptide Research Explained
How the cardiolipin-targeting tetrapeptide SS-31 works, what isolated-mitochondria, rodent and clinical studies have and have not shown, and practical notes for designing and handling SS-31 experiments.
Overview
Biochemical Characteristics
SS-31 features an alternating aromatic-cationic structure that enables rapid, energy-independent uptake into mitochondria. The dimethyltyrosine (Dmt) residue and D-arginine enhance stability and facilitate cardiolipin binding in experimental models.
Research Applications
Pathway / Mechanistic Context
Preclinical Research Summary
Form & Analytical Testing
Mechanisms of Action
Cardiolipin Binding - Selectively targets and stabilizes cardiolipin in the inner mitochondrial membrane
ROS Reduction - Decreases electron leak and mitochondrial reactive oxygen species production by 30-50%
Electron Transport Optimization - Improves cytochrome c-cardiolipin interaction and bioenergetic efficiency
Membrane Stabilization - Prevents cardiolipin peroxidation, cristae remodeling, and membrane damage
Research Applications
1Mitochondrial Dysfunction Research
Primary focus on restoring mitochondrial function in cellular and animal models.
Key Research Findings
- Reduces mitochondrial ROS production in cell and animal models
- Protects cardiolipin from peroxidation during oxidative stress
- Restores ATP synthesis capacity in aged or damaged mitochondria in animal models
- Prevents mitochondrial permeability transition pore opening
2Cardiolipin & Membrane Biology
Studies on inner mitochondrial membrane structure and function.
Key Research Findings
- Stabilizes cytochrome c-cardiolipin interactions
- Preserves cristae architecture under stress
- Maintains ETC complex assembly and supercomplex formation
- Protects membrane phospholipid integrity
3Ischemia-Reperfusion Research
Investigation of mitochondrial protection during oxygen deprivation and restoration.
Key Research Findings
- Reduces infarct size in cardiac ischemia models
- Preserves mitochondrial function during hypoxia
- Accelerates bioenergetic recovery after reperfusion
- Protects multiple organ systems in animal I/R injury models
Supporting Research & Bibliography
The following peer-reviewed publications support the research applications described above. References are provided for informational purposes to assist researchers in their literature review.
Total references: 4
Note: The information provided is for research reference only. It summarizes published in-vitro, animal and, where cited, human clinical studies of the compound; findings from those studies are not claims about this product. This product is intended for laboratory research purposes only. Not for human or veterinary use.
Common questions
- What purity is SS-31, and how is it tested?
- SS-31 is supplied at 99%+ purity. Each production lot is tested by an independent third-party laboratory, with HPLC for purity and mass spectrometry for identity. Published certificates can be looked up by the lot number printed on your vial in our COA library.
- Does SS-31 come with a Certificate of Analysis?
- Certificates are published online rather than printed in the box. You can view and download the certificate on this page before you buy, and match the lot number on your vial to its certificate in the COA library. Our guide on how to read a peptide COA explains each section.
- How fast does SS-31 ship?
- Orders placed before 2 PM EST ship the same day from the United States, with tracking and discreet packaging.
- How should SS-31 be stored?
- Store at -20°C. Our storage and handling guide covers temperature, light and moisture in more detail.
- What if independent testing doesn't confirm the stated purity?
- Our Purity Guarantee covers it: if independent testing does not confirm the stated purity, you get a full refund and a free replacement.
- Is SS-31 for human use?
- No. SS-31 is sold strictly for laboratory research use only. It is not for human or veterinary use, and we do not provide dosing or administration guidance.
Research Use Only: This product is intended for laboratory research purposes only. Not for human or veterinary use. By purchasing, you confirm that you are a qualified researcher and will use this product in accordance with all applicable regulations.