Certificate of Analysis
Each batch of MT-2 undergoes rigorous third-party testing to ensure purity and identity verification. The lab report for the latest batch is being finalized.
Melanotan II
99%+ purity, independently tested
Ships same day when ordered before 2 PM EST · tracked and discreet
Melanotan II (MT-2) is a synthetic cyclic heptapeptide analog of alpha-melanocyte stimulating hormone (α-MSH). This research-grade peptide is extensively studied for its interaction with melanocortin receptors (MC1R, MC3R, MC4R, MC5R) and melanogenesis pathways in laboratory settings.
99%+
10mg
Bundle & Save
Order before 2 PM EST, ships the same day. Fast, fully tracked, and sent in discreet, secure packaging. Free shipping on orders over $99.
Purity Guarantee. If independent third-party testing doesn't confirm our stated purity standards, you get a full refund plus a free replacement.
For Research Use Only
Intended for in-vitro research only. Not for human consumption. Must be 21+.
Specifications
Certificate of Analysis
Each batch of MT-2 undergoes rigorous third-party testing to ensure purity and identity verification. The lab report for the latest batch is being finalized.
Overview
Biochemical Characteristics
Melanotan II is a cyclic lactam peptide featuring a distinctive ring structure formed by an amide bond between aspartic acid and lysine side chains. This cyclic configuration enhances receptor binding affinity and metabolic stability compared to linear α-MSH analogs in experimental models.
Research Applications
Pathway / Mechanistic Context
Preclinical Research Summary
Form & Analytical Testing
Mechanisms of Action
MC1R Activation - Stimulates melanocyte-stimulating hormone receptor 1, promoting melanogenesis
MC3R/MC4R Binding - Interacts with central melanocortin receptors involved in energy homeostasis
Melanin Synthesis - Activates tyrosinase and melanin biosynthesis pathways in melanocytes
cAMP Signaling - Triggers cyclic AMP cascade through G-protein coupled receptor activation
Research Applications
1Melanogenesis Research
Melanotan II is primarily studied for its effects on melanin synthesis and melanocyte biology.
Key Research Findings
- Potent activation of MC1R in melanocyte models
- Stimulates eumelanin over pheomelanin production
- Increases tyrosinase activity and expression
- Enhances melanocyte dendricity and melanin transfer
2Melanocortin Receptor Pharmacology
Research explores receptor binding profiles and signaling mechanisms.
Key Research Findings
- High affinity for MC1R, MC3R, MC4R, and MC5R subtypes
- Cyclic structure confers enhanced receptor binding
- Useful tool for studying melanocortin receptor function
- Enables structure-activity relationship studies
3Pigmentation Pathway Studies
Studies investigate cellular mechanisms of pigmentation.
Key Research Findings
- Activates cAMP/PKA/CREB signaling cascade
- Upregulates MITF transcription factor
- Increases melanogenic enzyme expression
- Models for studying pigmentation disorders
Supporting Research & Bibliography
The following peer-reviewed publications support the research applications described above. References are provided for informational purposes to assist researchers in their literature review.
Total references: 4
Note: The information provided is for research reference only. It summarizes published in-vitro, animal and, where cited, human clinical studies of the compound; findings from those studies are not claims about this product. This product is intended for laboratory research purposes only. Not for human or veterinary use.
Common questions
- What purity is MT-2, and how is it tested?
- MT-2 is supplied at 99%+ purity. Each production lot is tested by an independent third-party laboratory, with HPLC for purity and mass spectrometry for identity. Published certificates can be looked up by the lot number printed on your vial in our COA library.
- Does MT-2 come with a Certificate of Analysis?
- Certificates are published online rather than printed in the box. You can view and download the certificate on this page before you buy, and match the lot number on your vial to its certificate in the COA library. Our guide on how to read a peptide COA explains each section.
- How fast does MT-2 ship?
- Orders placed before 2 PM EST ship the same day from the United States, with tracking and discreet packaging.
- How should MT-2 be stored?
- Store at -20°C. Our storage and handling guide covers temperature, light and moisture in more detail.
- What if independent testing doesn't confirm the stated purity?
- Our Purity Guarantee covers it: if independent testing does not confirm the stated purity, you get a full refund and a free replacement.
- Is MT-2 for human use?
- No. MT-2 is sold strictly for laboratory research use only. It is not for human or veterinary use, and we do not provide dosing or administration guidance.
Research Use Only: This product is intended for laboratory research purposes only. Not for human or veterinary use. By purchasing, you confirm that you are a qualified researcher and will use this product in accordance with all applicable regulations.