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IGF-1 LR3
Specialty Peptides

IGF-1 LR3

$150.00$120.0020% OFFIn StockChecking availability...

Long R3 Insulin-like Growth Factor-1 is an 83 amino acid analog of IGF-1. The LR3 modification provides enhanced stability and potency for research applications.

Purity

99%+

Size

1mg

1
COA Available
Lab Verified
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For Research Use Only (RUO)

This product is intended for in-vitro research applications only. Not for human or animal consumption, cosmetic use, or as a dietary supplement. All customers must be at least 21 years of age. It is the researcher's responsibility to handle materials in accordance with their institution's safety protocols and all applicable laws.

Specifications

Molecular Weight9,111 Da
Sequence83 Amino Acids
AppearanceWhite lyophilized powder
StorageStore at -20°C
SolubilitySoluble in sterile water

Certificate of Analysis

Each batch of IGF-1 LR3 undergoes rigorous third-party testing to ensure purity and identity verification. Download your COA instantly.

HPLC Purity Analysis
Mass Spectrometry Verification
Lot-Specific Documentation

Extended Research Applications & Mechanisms

Overview

IGF-1 LR3 is an 83-amino acid synthetic analog of human IGF-1 featuring an arginine substitution at position 3 and a 13-amino acid N-terminal extension. These modifications dramatically reduce binding to IGF binding proteins.

Biochemical Characteristics

Sequence: 83 amino acids (N-terminal extension + Arg3 substitution)
Molecular Formula: C₄₀₀H₆₂₅N₁₁₁O₁₁₅S₉
Molecular Weight: 9117.5 g/mol
CAS Number: 946870-92-4

Mechanisms of Action

1

IGF-1 Receptor Activation - High-affinity binding to IGF-1R with full agonist activity

2

IGFBP Resistance - Dramatically reduced binding to IGF binding proteins

3

PI3K/Akt Signaling - Activates phosphoinositide 3-kinase and downstream Akt pathway

4

Extended Half-Life - Prolonged biological activity due to reduced IGFBP sequestration

Research Applications

1Muscle Biology Research

Studies on muscle growth and regeneration.

Key Research Findings
  • Potent stimulator of muscle protein synthesis
  • Promotes satellite cell activation
  • Enhances muscle fiber hypertrophy
  • Supports muscle regeneration research

Note: The information provided is for research reference only. All research applications are based on in-vitro and animal studies. This product is intended for laboratory research purposes only. Not for human or veterinary use.

Research Use Only: This product is intended for laboratory research purposes only. Not for human or veterinary use. By purchasing, you confirm that you are a qualified researcher and will use this product in accordance with all applicable regulations.

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