Certificate of Analysis
Each batch of Glutathione undergoes rigorous third-party testing to ensure purity and identity verification. View the full lab report below.
Glutathione (L-Glutathione Reduced)
99%+ purity, independently tested · View COA
Ships same day when ordered before 2 PM EST · tracked and discreet
Reduced L-Glutathione (GSH) is a tripeptide composed of glutamic acid, cysteine, and glycine. This powerful antioxidant is essential for cellular research applications.
99%+
1500mg
Bundle & Save
Order before 2 PM EST, ships the same day. Fast, fully tracked, and sent in discreet, secure packaging. Free shipping on orders over $99.
Purity Guarantee. If independent third-party testing doesn't confirm our stated purity standards, you get a full refund plus a free replacement.
For Research Use Only
Intended for in-vitro research only. Not for human consumption. Must be 21+.
Specifications
Certificate of Analysis
Each batch of Glutathione undergoes rigorous third-party testing to ensure purity and identity verification. View the full lab report below.
Research background
Glutathione: Master Antioxidant in Research
Glutathione (GSH) is the most abundant non-protein thiol in mammalian cells. This guide covers how cells make and use it, how to read the GSH/GSSG couple, how to measure it without creating artifacts, the standard depletion and toxicology models, and how to handle the material in the lab.
Buy it as a stack
This compound is part of our curated sets. Same vials, same testing, lower total.
Overview
Biochemical Characteristics
Glutathione features a unique γ-peptide linkage that protects it from standard peptidase degradation. The cysteine thiol group (-SH) is the functional moiety responsible for its antioxidant and conjugation activities in experimental models.
Research Applications
Pathway / Mechanistic Context
Preclinical Research Summary
Form & Analytical Testing
Mechanisms of Action
Direct Antioxidant - Neutralizes reactive oxygen species (ROS) and reactive nitrogen species through thiol oxidation
Enzyme Cofactor - Essential substrate for glutathione peroxidases, S-transferases, and glyoxalases
Detoxification - Conjugates electrophilic toxins, xenobiotics, and drugs for Phase II elimination
Redox Signaling - Modulates protein function through S-glutathionylation of cysteine residues
Research Applications
1Oxidative Stress Research
Studies on cellular protection and antioxidant defense systems.
Key Research Findings
- Directly neutralizes reactive oxygen and nitrogen species
- Regenerates oxidized antioxidants including Vitamins C and E
- Protects against lipid peroxidation and membrane damage
- Reduces oxidative DNA damage and protein carbonylation
2Detoxification & Xenobiotic Metabolism
Research on Phase II metabolism and cellular detoxification.
Key Research Findings
- Essential substrate for glutathione S-transferase enzymes
- Conjugates electrophilic compounds for biliary/urinary excretion
- Modulates drug metabolism and chemoresistance
- Protects against heavy metal toxicity through chelation in cell and animal models
3Redox Signaling & Cell Biology
Investigation of glutathione in cellular signaling and homeostasis.
Key Research Findings
- GSH/GSSG ratio serves as cellular redox indicator
- S-glutathionylation regulates protein function
- Essential for mitochondrial function and integrity
- Modulates cell proliferation and apoptosis pathways
Supporting Research & Bibliography
The following peer-reviewed publications support the research applications described above. References are provided for informational purposes to assist researchers in their literature review.
Total references: 4
Note: The information provided is for research reference only. It summarizes published in-vitro, animal and, where cited, human clinical studies of the compound; findings from those studies are not claims about this product. This product is intended for laboratory research purposes only. Not for human or veterinary use.
Common questions
- What purity is Glutathione, and how is it tested?
- Glutathione is supplied at 99%+ purity. Each production lot is tested by an independent third-party laboratory, with HPLC for purity and mass spectrometry for identity. Published certificates can be looked up by the lot number printed on your vial in our COA library.
- Does Glutathione come with a Certificate of Analysis?
- Certificates are published online rather than printed in the box. You can view and download the certificate on this page before you buy, and match the lot number on your vial to its certificate in the COA library. Our guide on how to read a peptide COA explains each section.
- How fast does Glutathione ship?
- Orders placed before 2 PM EST ship the same day from the United States, with tracking and discreet packaging.
- How should Glutathione be stored?
- Store at -20°C. Our storage and handling guide covers temperature, light and moisture in more detail.
- What if independent testing doesn't confirm the stated purity?
- Our Purity Guarantee covers it: if independent testing does not confirm the stated purity, you get a full refund and a free replacement.
- Is Glutathione for human use?
- No. Glutathione is sold strictly for laboratory research use only. It is not for human or veterinary use, and we do not provide dosing or administration guidance.
Research Use Only: This product is intended for laboratory research purposes only. Not for human or veterinary use. By purchasing, you confirm that you are a qualified researcher and will use this product in accordance with all applicable regulations.