Certificate of Analysis
Each batch of RT-3 + Cagrilintide undergoes rigorous third-party testing to ensure purity and identity verification. The lab report for the latest batch is being finalized.
RT-3 + Cagrilintide Blend
99%+ purity, independently tested
Ships same day when ordered before 2 PM EST · tracked and discreet
Research blend pairing RT-3, a triple agonist at the GLP-1, GIP, and glucagon receptors, with Cagrilintide, a long-acting amylin analogue. 5mg of each compound in a single vial, for laboratory research into how incretin/glucagon signaling and amylin signaling interact in metabolic models.
99%+
5mg+5mg
Bundle & Save
Order before 2 PM EST, ships the same day. Fast, fully tracked, and sent in discreet, secure packaging. Free shipping on orders over $99.
Purity Guarantee. If independent third-party testing doesn't confirm our stated purity standards, you get a full refund plus a free replacement.
For Research Use Only
Intended for in-vitro research only. Not for human consumption. Must be 21+.
Specifications
Certificate of Analysis
Each batch of RT-3 + Cagrilintide undergoes rigorous third-party testing to ensure purity and identity verification. The lab report for the latest batch is being finalized.
Overview
Biochemical Characteristics
RT-3 is a hybrid peptide engineered for activity at GLP-1R, GIPR, and the glucagon receptor. Cagrilintide is a non-selective amylin receptor agonist carrying a C20 fatty diacid side chain that promotes albumin binding and an extended half-life in experimental models.
Research Applications
Pathway / Mechanistic Context
Preclinical Research Summary
Form & Analytical Testing
Mechanisms of Action
Triple Incretin/Glucagon Agonism - RT-3 activates GLP-1R, GIPR, and the glucagon receptor (GCGR)
Amylin Receptor Agonism - Cagrilintide activates amylin receptors (AMY1R/AMY3R) and the calcitonin receptor
Complementary Satiety Pathways - Incretin and amylin signaling act on distinct but overlapping central appetite circuits
Gastric Emptying & Glucagon Regulation - Amylin signaling slows gastric emptying and suppresses postprandial glucagon
Research Applications
1Incretin + Amylin Pathway Research
Studies on how amylin receptor agonism interacts with multi-receptor incretin signaling.
Key Research Findings
- Amylin and incretin receptors act through distinct receptor families
- Amylin + GLP-1 agonist co-administration has been studied in phase 2 trials
- Enables side-by-side comparison against RT-3 alone in the same model
- Supports investigation of additive versus overlapping effects
2Appetite & Energy Balance
Investigation of food intake, meal size, and energy expenditure.
Key Research Findings
- Amylin signaling reduces meal size through hindbrain pathways
- Glucagon receptor activation contributes to energy expenditure
- GLP-1R and GIPR activity influence central appetite regulation
- Slowed gastric emptying is a characteristic amylin effect
3Glucose Homeostasis
Studies on insulin, glucagon, and postprandial glucose dynamics.
Key Research Findings
- Incretin activity supports glucose-dependent insulin secretion
- Amylin signaling suppresses postprandial glucagon release
- Allows study of glucagon receptor agonism alongside amylin-mediated glucagon suppression
- Relevant to research models of impaired glucose tolerance
Supporting Research & Bibliography
The following peer-reviewed publications support the research applications described above. References are provided for informational purposes to assist researchers in their literature review.
Total references: 4
Note: The information provided is for research reference only. It summarizes published in-vitro, animal and, where cited, human clinical studies of the compound; findings from those studies are not claims about this product. This product is intended for laboratory research purposes only. Not for human or veterinary use.
Common questions
- What purity is RT-3 + Cagrilintide, and how is it tested?
- RT-3 + Cagrilintide is supplied at 99%+ purity. Each production lot is tested by an independent third-party laboratory, with HPLC for purity and mass spectrometry for identity. Published certificates can be looked up by the lot number printed on your vial in our COA library.
- Does RT-3 + Cagrilintide come with a Certificate of Analysis?
- Certificates are published online rather than printed in the box. You can view and download the certificate on this page before you buy, and match the lot number on your vial to its certificate in the COA library. Our guide on how to read a peptide COA explains each section.
- How fast does RT-3 + Cagrilintide ship?
- Orders placed before 2 PM EST ship the same day from the United States, with tracking and discreet packaging.
- How should RT-3 + Cagrilintide be stored?
- Store at -20°C. Our storage and handling guide covers temperature, light and moisture in more detail.
- What if independent testing doesn't confirm the stated purity?
- Our Purity Guarantee covers it: if independent testing does not confirm the stated purity, you get a full refund and a free replacement.
- Is RT-3 + Cagrilintide for human use?
- No. RT-3 + Cagrilintide is sold strictly for laboratory research use only. It is not for human or veterinary use, and we do not provide dosing or administration guidance.
Research Use Only: This product is intended for laboratory research purposes only. Not for human or veterinary use. By purchasing, you confirm that you are a qualified researcher and will use this product in accordance with all applicable regulations.